ِDezAzma

Maintenance of systemic redox homeostasis depends on the balance between antioxidant defense and oxidative injury, making plasma total antioxidant capacity a critical determinant of susceptibility to oxidative stress. Quantification of the ferric reducing ability of plasma (FRAP) demonstrated a significant increase in antioxidant capacity in suckling rats following administration of vitamin K1 (28, 56, or […]

Excessive pharmacological iron exposure represents a critical model of iron-induced oxidative stress and iron-mediated cellular toxicity, where uncontrolled redox reactions promote progressive molecular damage in circulating erythrocytes. The vulnerability of human red blood cells to oxidative injury is strongly associated with disruption of hemoglobin structure, impaired oxygen transport, and deterioration of membrane protein stability. Evaluation […]

Naghmeh Haddadi, Mehrzad Mirzania, and Hadi Ansarihadipour Syringic acid (SA) is a phenolic acid compound with antioxidant properties, investigated as a natural antioxidant agent in acute myeloid leukemia (AML), where oxidative stress contributes to disease progression and therapeutic resistance. Our investigation employed a sex- and age-matched design including healthy donors and AML patients at diagnosis, […]