ِDezAzma

Administration of excessive Vitamin K1 (phylloquinone) produced a pronounced age-dependent oxidative stress response characterized by distinct alterations in plasma antioxidant capacity, lipid peroxidation, and liver injury biomarkers in adult and weanling rats. Quantification of ferric reducing ability of plasma (FRAP) demonstrated that total antioxidant capacity remained unchanged in adult animals despite escalating vitamin K1 doses […]

Accurate evaluation of predicting the antioxidant status of human plasma by artificial neural network analysis represents an important advancement in clinical biochemistry, oxidative stress assessment, and precision medicine, particularly because simultaneous measurement of multiple oxidative and antioxidant biomarkers is labor-intensive, costly, and unsuitable for high-throughput clinical laboratories. To establish a reliable computational strategy, blood samples […]

Maintenance of systemic redox homeostasis depends on the balance between antioxidant defense and oxidative injury, making plasma total antioxidant capacity a critical determinant of susceptibility to oxidative stress. Quantification of the ferric reducing ability of plasma (FRAP) demonstrated a significant increase in antioxidant capacity in suckling rats following administration of vitamin K1 (28, 56, or […]

Occupational exposure to aluminum represents a significant source of aluminum-induced oxidative stress, where disruption of redox homeostasis accelerates oxidative injury to circulating blood components and compromises systemic antioxidant defense. Evaluation of blood samples obtained from hospital operating room personnel demonstrated that aluminum-mediated metal-catalyzed oxidation profoundly altered the biochemical balance between oxidants and antioxidants. Ferric reducing […]

Fatemeh Seif, Mohammad Reza Bayatiani, Hadi Ansarihadipour, Ghasem Habibi,Samira  Sadelaji Exposure to extremely low-frequency magnetic fields (ELFMF) has been implicated in the induction of systemic redox imbalance, particularly through disruption of erythrocyte stability and plasma antioxidant defenses; therefore, this experimental study was designed to evaluate the protective properties of Myrtus communis extract against ELFMF-induced oxidative […]

Mohamadreza Bayatiani, Hadi Ansarihadipour, Fatemeh Seif, Samira Sadelaji, Ghasem Habibi In the era of rapid technological development and increasing environmental exposure, understanding the biological consequences of physical and chemical stressors has become a major focus of biomedical research. Oxidative imbalance represents a central mechanism linking environmental challenges with cellular dysfunction, particularly through excessive reactive oxygen […]